I stumbled upon the challenge of trying to make a sharp capture of water droplets falling off an icicle today. The timing required a little observation and a lot of luck. To freeze the action, I had to increase the light sensitivity of my Canon Rebel by selecting ISO 6400. Naturally, this is going to introduce a great deal of chromatic and luminance noise. I did some selective post-processing via manual selections and multiple layers to optimize my file for print and web. Heavy noise reduction was only run on the background layer and my second pass of sharpening was only applied to the foreground.
Detail crop showing selective post-processing:
My finalized jpeg for web usage: